Breakthrough lung Scedosporium prolificans infection with multiple cavity lesions in a patient receiving voriconazole for probable invasive aspergillosis associated with monoclonal gammopathy of undetermined significance (MGUS).

نویسندگان

  • Rina Ohashi
  • Motoyasu Kato
  • Yoko Katsura
  • Hidenori Takekawa
  • Yoshito Hoshika
  • Tomonori Sugawara
  • Kaku Yoshimi
  • Shinsaku Togo
  • Tetsutaro Nagaoka
  • Kuniaki Seyama
  • Kazuhisa Takahashi
  • Koji Tsuchiya
  • Shigeki Misawa
  • Ken Kikuchi
چکیده

Breakthrough non- Aspergillus mold infections among patients receiving the anti-mold azole antifungal agents like voriconazole or posaconazole have been increasingly reported. We report a case of lung Scedosporium prolificans infection with multiple cavities in a 58-year-old man with monoclonal gammopathy of undetermined significance (MGUS) during voriconazole treatment for probable invasive aspergillosis. Cultures of repeated sputum specimens yielded the same fungus until his death 83 days after diagnosis. S. prolificans should be considered in patients with breakthrough infections receiving voriconazole.

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عنوان ژورنال:
  • Medical mycology journal

دوره 52 1  شماره 

صفحات  -

تاریخ انتشار 2011